Azoxystrobin acute toxicity study

JMPR 2008 Report Dec 11 - Food and Agriculture ...

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Azoxystrobin has low acute toxicity when administered by the oral, dermal or inhalation routes. The median lethal dose (LD50) in rats treated orally was > 5000 mg/kg bw. The LD50 in rats treated dermally was > 2000 mg/kg bw. ... In a 1-year study of toxicity in dogs, the NOAEL was 25 mg/kg bw

JMPR 2008 Report Dec 11 - Food and Agriculture ...

Azoxystrobin - Cornell University

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Azoxystrobin is a broad spectrum fungicide with activity against several diseases on many edible crops and ornamental plants. Some diseases controlled or prevented are rice blast, rusts, downy mildew, powdery mildew, late blight, apple scab, and Septoria (1, 4). TOXICOLOGICAL EFFECTS ACUTE TOXICITY The acute rat oral LD50 was >5,000 mg/kg.

Azoxystrobin - Cornell University

Pesticide Fact Sheet - US EPA

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of low to very low acute toxicity. The Technical is also of low to very low subchronic and chronic toxicity and is not likely to be a carcinogen. The only Toxicology data gaps that exist for Azoxystrobin use on Turf are upgrading of the Acute Oral Neurotoxicity (Rat) study (GRN 81-8) and the Subchronic Neurotoxicity (Rat) study

Pesticide Fact Sheet - US EPA

Acute toxicity of the fungicide azoxystrobin on the diatom ...

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Azoxystrobin (AZ) is an effective broad-spectrum fungicide. Due to its extensive application, AZ is detectable in aquatic ecosystems and thus influences aquatic organisms. In this study, the acute toxicity (96 h) of AZ at concentrations of 1.0 mg/L and 5.0 mg/L …

Acute toxicity of the fungicide azoxystrobin on the diatom ...

Acute toxicity of the fungicide azoxystrobin on the diatom ...

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This study investigated the short-term toxicity of azoxystrobin (AZ), one of strobilurins used as an effective fungicidal agent to control the Asian soybean rust, on aquatic unicellular algae ...

Acute toxicity of the fungicide azoxystrobin on the diatom ...

5.21 TEBUCONAZOLE (189) TOXICOLOGY

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Tebuconazole 309 In a two-generation study of reproductive toxicity in rats, the reproductive parameters were not affected at doses up to 1000 ppm (equal to 72.3 mg/kg bw per day), the highest dose tested.

5.21 TEBUCONAZOLE (189) TOXICOLOGY

Azoxystrobin | C22H17N3O5 - PubChem

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/LABORATORY ANIMALS: Acute Exposure/ In a study of acute toxicity after inhalation, groups of five male and five female young adult Wistar rats (Alpk:APfSD) were exposed nose-only to azoxystrobin (purity, 96.2%) for 4 hr at a concentration of 0.2, 0.5, or 0.8 mg/L.

Azoxystrobin | C22H17N3O5 - PubChem

Pesticides Fact Sheet for Azoxystrobin 1997 - EPA

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----- Azoxystrobin is additionally of low acute and chronic toxicity to humans and is unlikely to be a carcinogen. It is also of low acute and chronic toxicity to birds, mammals, and bees. Facts unfavorable to Azoxystrobin are that it does not control Dollar Spot, a major Turf pest.

Pesticides Fact Sheet for Azoxystrobin 1997 - EPA

Azoxystrobin - Pesticide Tolerance 3/99 - Cornell University

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1. Acute toxicity. The acute oral toxicity study in rats of technical azoxystrobin resulted in an LD50 of > 5,000 milligrams/kilogram (mg/kg) (limit test) for both males and females. The acute dermal toxicity study in rats of technical azoxystrobin resulted in an LD50 of > 2,000 mg/kg (limit dose).

Azoxystrobin - Pesticide Tolerance 3/99 - Cornell University

Captan - US EPA

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Acute dermal exposure to captan may cause dermatitis and conjunctivitis in humans. (2) Ingestion of large quantities of captan may cause vomiting and diarrhea in humans. (4) Acute animal tests in rats and mice have demonstrated captan to have low to moderate acute toxicity by inhalation or dermal exposure and low acute toxicity by oral exposure.

Captan - US EPA

Index for Azoxystrobin (PC Code 128810) | Pesticides | US EPA

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Index of Cleared Science Reviews for Azoxystrobin (PC Code 128810) Index of Cleared Science Reviews for Azoxystrobin (PC Code 128810) ... Repeated dose dermal - rat (82-2) 21-day dermal toxicity study in the rat. MRID 43678137. Document (PDF) (450 KB PDF). April 18, 1996. Review. 27 Page(s). ... 72-2 Acute LC50 test with a freshwater ...

Index for Azoxystrobin (PC Code 128810) | Pesticides | US EPA

Federal Register :: Azoxystrobin; Pesticide Tolerances

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In the present study, the acute and chronic physiological effects of the strobilurin fungicide azoxystrobin on three clones of D. magna originating from different Danish lakes were evaluated.

Federal Register :: Azoxystrobin; Pesticide Tolerances

Chronic aquatic effect assessment for the fungicide ...

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Reproductive toxicity of azoxystrobin to adult zebrafish. Reproductive toxicity was tested according to Organization for Economic Co-operation and Development (OECD) Guideline 229 (OECD 229, 2012) and a method from a previous study (Bluthgen et al., 2013) with some modifications. The experiment consisted of a 14-day pre-exposure and a 21-day ...

Chronic aquatic effect assessment for the fungicide ...

Reproductive toxicity of azoxystrobin to adult zebrafish ...

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In this study, the early life stage of grass carp (Ctenopharyngodon idella), which is one of the most important aquaculture species in China, was chosen to measure the acute toxicity of three common strobilurin-derived fungicides (trifloxystrobin (TFS), azoxystrobin (AZ) and kresoxim-methyl (KM)).

Reproductive toxicity of azoxystrobin to adult zebrafish ...

Toxic effects of three strobilurins (trifloxystrobin ...

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These compounds have a relatively low acute toxicity; most have a reported LD 50 oral of over 5,000 mg/kg, except orysastrobin and metominostrobin, with LD 50 of 356 mg/kg and 708 mg/kg, respectively.13,15 Few human data are available, though several separate incidents in July 2007 were reported by the CDC. All reports were based on pyraclostrobin.

Toxic effects of three strobilurins (trifloxystrobin ...

Recognition and Management of Pesticide Poisonings: Sixth ...

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Azoxystrobin has low acute toxicity via the oral, dermal and inhalation routes of exposure. It is not an eye or skin irritant and is not a skin sensitizer. Dietary administration of azoxystrobin to rats resulted in decreased body weights, decreased food intake and utilization, increased diarrhea and other clinical toxicity observations ...

Recognition and Management of Pesticide Poisonings: Sixth ...

Federal Register :: Azoxystrobin; Pesticide Tolerances

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No photo‐enhanced toxicity was observed for either C. dubia or L. siliquoidea exposed to ultraviolet light in control water following azoxystrobin tests. The results of the present study indicate chronic effects of azoxystrobin on 3 of 4 invertebrates tested at environmentally relevant concentrations.

Federal Register :: Azoxystrobin; Pesticide Tolerances

Chronic toxicity of azoxystrobin to freshwater amphipods ...

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study is repeated with either a rainbow trout (preferred) or bluegill sunfish and found to be acceptable, the data gap for the fathead minnow acute toxicity test would be eliminated. However, if the early-life stage study is repeated with the fathead minnow, then the data gap for the fathead minnow acute …

Chronic toxicity of azoxystrobin to freshwater amphipods ...

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

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ecosystems. Environmental concentrations of the fungicide azoxystrobin have been reported up to 4.6µg/L in the United States and 30 µg/L in Europe. The objective of the present study was to evaluate the chronic toxicity of azoxystrobin in water-only exposures with an amphipod

UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

Chronic toxicity of azoxystrobin to freshwater amphipods ...

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Abstract. Strobilurins constitute a new class of fungicides that is the most widely used in the world. The present study was conducted to investigate the aquatic toxicity of 3 common strobilurin fungicides (kresoxim-methyl, pyraclostrobin, and trifloxystrobin) to Daphnia magna.The neonate acute immobilization test showed that the 48-h 50% effective concentration (EC50) values of kresoxim ...

Chronic toxicity of azoxystrobin to freshwater amphipods ...

Toxicity of three strobilurins (kresoxim‐methyl ...

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However, animals in the high dose group for this study showed excessive toxicity; furthermore, the high dose exceeded the Maximum Tolerated Dose determined in the 90-day range finding study. No treatment-related tumors were seen in female mice in this mouse chronic feeding study. No tumors were noted in a chronic rat study.

Toxicity of three strobilurins (kresoxim‐methyl ...

TRIVAPRO FUNGICIDE - Amazon Simple Storage Service

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MATERIAL SAFETY DATA SHEET UPDATES AVAILABLE AT WWW.GREENBOOK.NET 1 HERITAGE FUNGICIDE ... Acute Toxicity/Irritation Studies (Finished Product) Ingestion: Practically Non-Toxic ... Azoxystrobin: In a rat 90-day feeding study, liver tox-icity was observed at …

TRIVAPRO FUNGICIDE - Amazon Simple Storage Service

MATERIAL SAFETY DATA SHEET UPDATES AVAILABLE AT WWW ...

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Captan is a fungicide used on fruits, vegetables, and ornamentals. Acute (short-term) dermal exposure to captan may cause dermatitis and conjunctivitis in humans. Ingestion of large quantities of captan may cause vomiting and diarrhea in humans.

MATERIAL SAFETY DATA SHEET UPDATES AVAILABLE AT WWW ...

Captan | C9H8Cl3NO2S - PubChem

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5/28/2011 · In this study, we performed toxicity tests with six non-target aquatic fungi and two oomycetes (Pythium) and determined the effect of seven fungicides with different modes of actions. Our results demonstrated that fungicide HC5 values calculated on basis of species sensitivity distributions (SSDs) constructed with acute toxicity data of other ...

Captan | C9H8Cl3NO2S - PubChem

Effects of Seven Fungicides on Non-Target Aquatic Fungi

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Toxicity, Sublethal Effects, and Potential Modes of Action of Select Fungicides on Freshwater Fish and Invertebrates . By Adria A. Elskus . 1BAbstract . Despite decades of agricultural and urban use of fungicides and widespread detection of these pesticides in surface waters, relatively few data are available on the effects of fungicides on ...

Effects of Seven Fungicides on Non-Target Aquatic Fungi

Toxicity, Sublethal Effects, and Potential Modes of Action ...

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finding study. No treatment-related tumors were seen in female mice in this mouse chronic feeding study. No tumors were noted in a chronic rat study. Azoxystrobin : Did not show reproductive toxicity effects in animal experiments. Propiconazole: None observed. Chemical Name NTP/IARC/OSHA Carcinogen 1,2-Propanediol No Dermal, Inhalation

Toxicity, Sublethal Effects, and Potential Modes of Action ...

QUILT® FUNGICIDE - CDMS

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2. The acute toxicity reported on this page is of the pure chemical ingredient only and may not reflect the acute toxicity of individual pesticide products. To view acute toxicity of individual products, click on 'View Products' link in the 'Chemical Identification' section above.

QUILT® FUNGICIDE - CDMS

2,4-D - toxicity, ecological toxicity and regulatory ...

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Acute Toxicity and Etho-toxicity of Three Insecticides ... Effects of pond water, sediment, and sediment extracts from Minnesota and. Vermont, USA, on ... Ceylon Journal of Science, 40(2), 133â 140.

2,4-D - toxicity, ecological toxicity and regulatory ...

Acute toxicity of three strobilurin fungicide formulations ...

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Toxicity Study •Azoxystrobin toxicity: •Tadpoles: 0.5mg/L (Johanssen et al. 2005), No toxicity (Belden et al. 2009) •Freshwater Fish Acute Toxicity (EPA Fact Sheet) •Rainbow Trout LC50=0.47 ppm, Highly toxic •Bluegill LC50=1.1 ppm, Moderately toxic

Acute toxicity of three strobilurin fungicide formulations ...

Agrichemicals in the Rainwater Basin: Presence, timing ...

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tration only, excluding its metabolites, which our study was in line with. Similar with chlorothalonil, azoxystrobin is the derivation from the naturally occurring fungicide with a broad spectrum of systemic activity for controlling fungal crop patho-gens. Azoxystrobin, likewise …

Agrichemicals in the Rainwater Basin: Presence, timing ...

Residues and dissipation of chlorothalonil and ...

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Azoxystrobin; Pesticide Tolerances, 53174-53179 [E9-24813] ... Azoxystrobin has a low acute toxicity via the oral, dermal and inhalation routes of exposure. It is not an eye or skin irritant and is not a skin sensitizer. ... In the rat developmental toxicity study, diarrhea, urinary incontinence and salivation were observed in maternal animals ...

Residues and dissipation of chlorothalonil and ...

Azoxystrobin; Pesticide Tolerances, 53174-53179 [E9-24813 ...

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7/13/2010 · Acute toxicity tests based on the criteria of immobilization were performed on egg‐carrying D. magna, and sublethal concentrations of 0.1, 1.0, and 10 µg/L cypermethrin and 0.5, 1.0, and 2.0 mg/L azoxystrobin were established. At a concentration as low as 0.1 µg/L cypermethrin, the 5% effective concentration after 24 h of exposure (EC5,24h ...

Azoxystrobin; Pesticide Tolerances, 53174-53179 [E9-24813 ...

Early signs of lethal effects in Daphnia magna ...

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cHRoNIc/SubcHRoNIc ToxIcITY STuDIES: Azoxystrobin: in a rat 90-day feeding study, liver toxicity was ob-served at 2,000 ppm. This was manifest asgross distension of the bile duct, increased numbers of lining cells and inflammation of the duct. No toxicologically significant …

Early signs of lethal effects in Daphnia magna ...
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